Luther faced St. Mary's University (MN) for its season opener at the Minnesota State University Dome. The Norse scored five in the top of the third, but were unable to hold the Cardinals in check and were defeated by a final of 9-6. The Cardinals scored two in both the third and fourth frames, one in the fifth and four in the sixth enroute to the victory. Luther's final run came in the top of the sixth.

Riley Sauser led the Norse attack with a 2-for-3 performance, driving in two runs and scoring twice. Jaydan Clayton also had a multiple hit game going 3-for-3. Madi Urfer and Alison Martinez were both credited with an rbi.

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